Low-Dose Sertraline Improves Receptive Language in Children with Fragile X Syndrome when Eye Tracking Methodology is used to Measure Treatment Outcome
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چکیده
Submit Manuscript | http://medcraveonline.com Abbreviations: FXS: Fragile X syndrome; PVET: Passive-Viewing Eye Tracking Task; MSEL: Mullen Scales of Early Learning; PLS: Preschool Language Scale; FMR1: Fragile X Mental Retardation 1; FMRP: FMR1 Protein; SSRI: Selective Serotonin Reuptake Inhibitor; ASD: Autism Spectrum Disorder; CA: Chronological Age; MA: Mental Age; CDI: MacArthur-Bates Communicative Development Inventory Background
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Sertraline May Improve Language Developmental Trajectory in Young Children with Fragile X Syndrome: A Retrospective Chart Review
Young children with fragile X syndrome (FXS) often experience anxiety, irritability, and hyperactivity related to sensory hyperarousal. However, there are no medication recommendations with documented efficacy for children under 5 years old of age with FXS. We examined data through a chart review for 45 children with FXS, 12-50 months old, using the Mullen Scales of Early Learning (MSEL) for ba...
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